Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.37 |
| ▸ | CYBB | P04839 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822375 | 1.00 | LMNA (0.42) | LMNAALDH1A1PTGS2OPRK1PDE4D | |
| SCHEMBL11823612 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1PTGS2OPRK1PDE4D | |
| SCHEMBL15846800 | 0.82 | SRD5A2 (0.58) | LMNAALDH1A1PTGS2OPRK1PDE4D | |
| SCHEMBL11827754 | 0.82 | NOX1 (0.42) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL11827768 | 0.82 | NOX1 (0.42) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL27791546 | 0.81 | ALDH1A1 (0.49) | LMNAALDH1A1PTGS2OPRK1PDE4D | |
| SCHEMBL11828287 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1PTGS2OPRK1PDE4D | |
| SCHEMBL28354228 | 0.75 | AKR1C1 (0.50) | ALDH1A1PTGS2SRD5A2MAPTMEN1 | |
| SCHEMBL27794501 | 0.73 | SRD5A2 (0.58) | LMNAALDH1A1SRD5A2MAPTMEN1 | |
| SCHEMBL11836394 | 0.72 | ALOX5 (0.38) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975403-A | Sulfur-containing ring compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-08-17 | — | — | US | disclosed |