Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074739 | 0.78 | POLB (1.00) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL11823704 | 0.76 | POLB (0.59) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL11824788 | 0.74 | POLB (0.80) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL11833227 | 0.71 | APOBEC3G (0.39) | POLBAPOBEC3GCYP1A2LMNAHTT | |
| SCHEMBL11818048 | 0.70 | POLB (0.80) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL11834863 | 0.69 | POLB (0.70) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL24601859 | 0.69 | POLB (0.79) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 | |
| SCHEMBL5691388 | 0.66 | LMNA (0.46) | POLBAPOBEC3GCYP1A2LMNAHTT | |
| SCHEMBL5692220 | 0.66 | ALDH1A1 (0.69) | POLBAPOBEC3GCYP1A2SMN1; SMN2HPGD | |
| SCHEMBL10517955 | 0.65 | HTT (0.56) | POLBAPOBEC3GLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979369-A | DIENE POLYMER | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |