Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818048 | 0.89 | POLB (0.80) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL11824788 | 0.89 | POLB (0.80) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL24601859 | 0.88 | POLB (0.79) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL11834863 | 0.83 | POLB (0.70) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL11824926 | 0.82 | POLB (0.68) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL11817997 | 0.82 | POLB (0.68) | POLBAPOBEC3GLMNAKDM4EHTT | |
| SCHEMBL24339463 | 0.80 | POLB (0.64) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL1885381 | 0.79 | POLB (0.65) | POLBAPOBEC3GLMNAKDM4ETSHR | |
| SCHEMBL11822467 | 0.78 | POLB (0.61) | POLBAPOBEC3GLMNAHTTMEN1 | |
| SCHEMBL11825058 | 0.78 | POLB (0.62) | POLBAPOBEC3GLMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319039-A2 | PYRIMIDINE DERIVATIVES AS HARDNESS STABILIZERS | Flexsys America L.P. (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2001070870-A2 | PYRIMIDINE DERIVATIVES AS HARDNESS STABILIZERS | FLEXSYS AMERICA L.P. (US) | 2001-09-27 | — | — | WO | claimed |
| CN-113993719-B | Trisulfide compound | 住友化学株式会社 | 2024-01-02 | — | — | CN | disclosed |
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-11760864-B2 | Trisulfide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-19 | — | — | US | disclosed |
| US-11692088-B2 | Rubber composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11692088-B2 | Rubber composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| CN-111094428-B | Rubber composition | 住友化学株式会社 | 2022-07-15 | — | — | CN | disclosed |
| US-11370776-B2 | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | INFLAZOME LIMITED (IE) | 2022-06-28 | — | — | US | disclosed |
| US-11370776-B2 | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | INFLAZOME LIMITED (IE) | 2022-06-28 | — | — | US | disclosed |
| US-20220119623-A1 | VULCANIZED RUBBER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-04-21 | — | — | US | disclosed |
| EP-3256462-B1 | SUBSTITUTED 2-THIOIMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-10368545-B2 | Substituted 2-thioimidazolylcarboxamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-3495413-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2019-06-12 | — | — | EP | disclosed |
| EP-3495414-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-20190169404-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20190169400-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| WO-2019034686-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019008029-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-01-10 | — | — | WO | disclosed |
| US-20180007900-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370776-B2 | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | NLRP3, NOD1, NLRP1 | POLB 4687/4885APOBEC3G 3298/4885LMNA 1137/4885 |
| US-11760864-B2 | Trisulfide compound | TST, TMT1A, SULT1A1 | POLB 1950/4885APOBEC3G 2686/4885LMNA 3789/4885 |
| US-10368545-B2 | Substituted 2-thioimidazolylcarboxamides as pesticides | TSNAX, DDT, PTMS | POLB 4413/4885APOBEC3G 2295/4885LMNA 2129/4885 |
| US-20180007900-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | TSNAX, DDT, PTMS | POLB 4413/4885APOBEC3G 2295/4885LMNA 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.