Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.65 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49240 | 0.80 | CA2 (0.42) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.79 | SMN1; SMN2 (1.00) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.79 | SMN1; SMN2 (1.00) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL864242 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL20660368 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11859223 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL7075597 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL4170581 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343307 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11857289 | 0.77 | SMN1; SMN2 (0.95) | CA2ALDH1A1SMN1; SMN2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935160-A | OXIDATION RESISTANCE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-01-27 | — | — | US | disclosed |