SCHEMBL11822980

SCHEMBL11822980

COc1ccc(-c2nnc(-c3ccccc3C(=O)O)o2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.68
RAB9A P51151 6/20 0.68
ABCG2 Q9UNQ0 2/20 0.62
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 5/20 0.55
HPGD P15428 5/20 0.55
KMT2A Q03164 2/20 0.55
HSD17B10 Q99714 4/20 0.55
MEN1 O00255 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
CACNA1B Q00975 1/20 0.55
APBA1 Q02410 1/20 0.55
MAPT P10636 2/20 0.54
TP53 P04637 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
USP2 O75604 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11611972 0.85 RAB9A (0.64) NPC1RAB9AABCG2KDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL11613889 0.84 RAB9A (0.62) NPC1RAB9AABCG2KDM4EALDH1A1
SCHEMBL269580 0.82 SMN1; SMN2 (0.70) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL29121418 0.82 RAB9A (1.00) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL11341017 0.82 EGFR (0.52) NPC1RAB9AABCG2KDM4EALDH1A1
SCHEMBL32674532 0.82 EGFR (0.52) NPC1RAB9AABCG2KDM4EALDH1A1
SCHEMBL11615095 0.81 ALDH1A1 (0.58) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL11614458 0.81 RAB9A (0.65) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL12798151 0.81 CSNK2A2 (0.73) NPC1RAB9AABCG2KDM4EALDH1A1
SCHEMBL11822985 0.81 RAB9A (0.67) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3964896-A Oxadiazole benzoic acid derivatives as herbicides UNIROYAL, INC. (US) 1976-06-22 US disclosed