Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11823944 | 0.98 | ALDH1A1 (0.45) | ALDH1A1GAATDP1ALOX15HTT | |
| SCHEMBL11822532 | 0.87 | MAPT (0.46) | ALDH1A1GAAGOT1MAPTADORA3 | |
| SCHEMBL11824349 | 0.84 | SYK (0.43) | ALDH1A1GAATDP1GOT1MAPT | |
| SCHEMBL11827111 | 0.80 | NPC1 (0.40) | ALDH1A1GAAHTTMAPTPTGS1 | |
| SCHEMBL11823326 | 0.80 | EPHX2 (0.40) | ALDH1A1GAATDP1MAPTMEN1 | |
| SCHEMBL11821784 | 0.80 | MAPT (0.48) | ALDH1A1GAATDP1HTTMAPT | |
| SCHEMBL11821391 | 0.79 | ALDH1A1 (0.52) | ALDH1A1GAATDP1ALOX15HTT | |
| SCHEMBL14428238 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAATDP1ALOX15HTT | |
| SCHEMBL15096265 | 0.73 | SYK (0.68) | ALDH1A1GAATDP1ALOX15HTT | |
| SCHEMBL11820367 | 0.73 | ALDH1A1 (0.36) | ALDH1A1GAATDP1GOT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | claimed |
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |