Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827308 | 0.87 | MAOB (0.53) | MAOBHCAR2MMECYP2A6BRS3 | |
| SCHEMBL11823728 | 0.85 | MAOB (0.54) | MAOBHCAR2MMECYP2A6BRS3 | |
| SCHEMBL11823662 | 0.84 | MMP12 (0.58) | MMEMMP2MMP9MMP12MMP13 | |
| SCHEMBL11823054 | 0.84 | CSNK2A1 (0.53) | HCAR2MMEMMP2MMP9MMP12 | |
| SCHEMBL11824134 | 0.82 | MAOB (0.48) | MAOBHCAR2MMEMMP12FFAR1 | |
| SCHEMBL11833616 | 0.82 | DPP4 (0.46) | CYP2A6ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL11834955 | 0.81 | MAOB (0.47) | MAOBHCAR2MMEITGB1ITGA4 | |
| SCHEMBL11827051 | 0.81 | MAOB (0.49) | MAOBHCAR2MMECYP2A6BRS3 | |
| SCHEMBL11829300 | 0.81 | MAOB (0.49) | MAOBHCAR2MMECYP2A6BRS3 | |
| SCHEMBL11826267 | 0.81 | MAOB (0.49) | MAOBHCAR2MMECYP2A6BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |