Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837086 | 0.87 | BACE1 (0.44) | MMP2HCAR2KMT2AMMP9MMP12 | |
| SCHEMBL11829343 | 0.86 | CSNK2A1 (0.53) | CSNK2A1ADRB1ADRB3MMP2MMP3 | |
| SCHEMBL11837826 | 0.84 | PTGS1 (0.49) | MMP2MMP3HCAR2KMT2A | |
| SCHEMBL11827837 | 0.84 | PPARG (0.49) | MMP2MMP3HCAR2KMT2AMMP9 | |
| SCHEMBL11832248 | 0.84 | KMT2A (0.39) | CSNK2A1MMP2KMT2AMMP9MMP12 | |
| SCHEMBL11829226 | 0.84 | FOLH1 (0.41) | CSNK2A1MMP2KMT2AMMP9MMP12 | |
| SCHEMBL11828303 | 0.84 | ADAMTS4 (0.41) | CSNK2A1MMP2KMT2AMMP9MMP12 | |
| SCHEMBL11821466 | 0.84 | CD274 (0.39) | MMP2MMP3KMT2AMMP9MMP12 | |
| SCHEMBL11834253 | 0.84 | CSNK2A1 (0.46) | CSNK2A1ADRB1ADRB3MMP2MMP3 | |
| SCHEMBL11823516 | 0.84 | MAOB (0.54) | MMP2HCAR2KMT2AMMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |