Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823516 | 0.82 | MAOB (0.54) | KMT2AMEN1ALDH1A1NPSR1CYP2A6 | |
| SCHEMBL11824543 | 0.82 | KMT2A (0.47) | KMT2ASLC6A4SLC6A3PPARGPPARA | |
| SCHEMBL11829514 | 0.79 | ALDH1A1 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL11836653 | 0.79 | PTGER4 (0.49) | KMT2A | |
| SCHEMBL11831432 | 0.77 | DPP4 (0.40) | DPP4KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9890641 | 0.76 | CXCL8 (0.57) | DPP4CXCL8AKR1B10UGT1A9TRPA1 | |
| SCHEMBL7372199 | 0.76 | PPARG (0.50) | KMT2APPARGPPARANPC1RAB9A | |
| SCHEMBL3433828 | 0.76 | PPARG (0.50) | KMT2APPARGPPARANPC1RAB9A | |
| SCHEMBL11830140 | 0.76 | PPARG (0.44) | KMT2APPARGPPARAPTGS2TAAR1 | |
| SCHEMBL27412483 | 0.75 | SLC16A3 (0.43) | SLC6A2SLC6A4SLC6A3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |