Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5511893 | 0.96 | MAPT (0.68) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30608268 | 0.85 | NPC1 (0.73) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30608267 | 0.85 | MAPT (0.61) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30608270 | 0.85 | NPC1 (0.66) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8805009 | 0.84 | MAPT (1.00) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11823271 | 0.84 | EYA3 (0.66) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL716903 | 0.83 | RAB9A (0.74) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30608274 | 0.83 | KDM4E (0.72) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16581242 | 0.82 | NPC1 (0.57) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7437950 | 0.82 | SMN1; SMN2 (0.69) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983245-A | CORONARY VASODILATORS | SMITHKLINE CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |