Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608268 | 0.88 | NPC1 (0.73) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL30608270 | 0.87 | NPC1 (0.66) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL11823271 | 0.86 | EYA3 (0.66) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL3699309 | 0.85 | SMN1; SMN2 (0.69) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL30608264 | 0.85 | MAPT (0.69) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL16581242 | 0.85 | NPC1 (0.57) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL30608273 | 0.85 | PTPN1 (0.59) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL31683105 | 0.82 | NPC1 (0.59) | SMN1; SMN2AHRNPC1RAB9AMAPT | |
| SCHEMBL11823964 | 0.82 | MAPT (0.73) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL7438307 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2AHRNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551662-A1 | Benzofuranyl- and thiophenylmethylthio-alcanecarboxylic acid derivatives | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |