Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 0.79 |
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.51 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.51 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447989 | 0.93 | RAB9A (0.87) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL5445468 | 0.90 | RAB9A (0.82) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL1448496 | 0.89 | RAB9A (0.79) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL14398440 | 0.85 | RAB9A (0.73) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL340809 | 0.83 | CYP1A2 (1.00) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL31136068 | 0.83 | CYP1A2 (1.00) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL14596729 | 0.83 | RAB9A (0.68) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL1447699 | 0.82 | RAB9A (0.68) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL11768536 | 0.81 | RAB9A (0.72) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL11771856 | 0.81 | RAB9A (0.72) | RAB9ANPC1POLBHSP90AA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144170-A1 | Fc RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | THE MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH LTD (AU) | 2011-06-16 | — | — | US | disclosed |
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144170-A1 | Fc RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | FCGR1A, FCGR2A, FCGR3B | RAB9A 1641/4885NPC1 1602/4885POLB 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.