Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 10/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831630 | 0.88 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL8928409 | 0.88 | OPRK1 (0.52) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11829520 | 0.83 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11870422 | 0.82 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11831027 | 0.79 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL7315271 | 0.78 | PTAFR (0.41) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11508083 | 0.73 | PTAFR (0.36) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11511588 | 0.72 | PTAFR (0.38) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11508751 | 0.72 | PTAFR (0.34) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| Clotiazepam SCHEMBL44592 | 0.70 | OPRK1 (0.63) | OPRK1PDE4DMEN1KMT2APTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965111-A | TRIQUALIZER, SLEEP INDUCER, ANTIELEPTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-06-22 | — | — | US | disclosed |