Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 11/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824366 | 0.88 | OPRK1 (0.51) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11511588 | 0.85 | PTAFR (0.38) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11831630 | 0.83 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11870422 | 0.83 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11829520 | 0.80 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11831027 | 0.80 | OPRK1 (0.46) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL11510628 | 0.76 | ALOX12 (0.38) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL7315271 | 0.76 | PTAFR (0.41) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11388559 | 0.74 | GABRA1 (0.39) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11619444 | 0.74 | GABRA1 (0.46) | OPRK1PDE4DGABRA1GABRA5GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-3965111-A | TRIQUALIZER, SLEEP INDUCER, ANTIELEPTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
| US-3952006-A | Thiophene derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |