SCHEMBL28260280

SCHEMBL28260280

NCc1ccccc1C1CO1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
PNMT P11086 3/20 0.40
DPP4 P27487 2/20 0.38
HTR2C P28335 9/20 0.35
HTR2A P28223 8/20 0.35
RET P07949 1/20 0.35
HRH1 P35367 1/20 0.35
HTR2B P41595 8/20 0.35
CYP2A6 P11509 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283570 0.89 TSHR (0.57) TSHRHTR2CHTR2AHTR2BSLC6A2
SCHEMBL9008384 0.86 PNMT (0.33) TSHRPNMTDPP4HTR2CHTR2A
SCHEMBL27997001 0.80 PKM (0.36) TSHRPNMTDPP4SLC6A2SLC6A4
SCHEMBL28870581 0.80 KDM4E (0.30)
SCHEMBL8358228 0.79 CTSB (0.49) TSHRSLC6A2SLC6A4
SCHEMBL31503923 0.79 TSHR (0.41) TSHRHTR2CHTR2AHTR2B
SCHEMBL7049394 0.79 TSHR (0.41) TSHRHTR2CHTR2AHTR2B
SCHEMBL8595905 0.78 PNMT (0.33) PNMTDPP4SLC6A2SLC6A4SLC6A3
SCHEMBL28133128 0.78 TSHR (0.39) TSHRDPP4SLC6A2SLC6A4SLC6A3
SCHEMBL31325361 0.78 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180482-A Vegetable oil polyalcohol and preparation method and application thereof 南京工业大学 2019-01-11 CN claimed
CN-109180482-A Vegetable oil polyalcohol and preparation method and application thereof 南京工业大学 2019-01-11 CN disclosed