Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833599 | 0.84 | MAPT (0.40) | MAPTGAARAB9AALDH1A1POLB | |
| SCHEMBL11818693 | 0.83 | MAPT (0.46) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL11823559 | 0.82 | MAPT (0.50) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL11833640 | 0.80 | ALDH1A1 (0.46) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL11821784 | 0.74 | MAPT (0.48) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL11821832 | 0.74 | RAB9A (0.52) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL11833039 | 0.71 | GAA (0.41) | MAPTGAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11823585 | 0.69 | GAA (0.51) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL9754619 | 0.68 | MAPT (0.57) | MAPTGAARAB9AALDH1A1HTT | |
| SCHEMBL4933031 | 0.68 | MAPT (0.57) | MAPTGAARAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |