Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823547 | 0.81 | LMNA (0.43) | GAAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL11825813 | 0.80 | PTGS1 (0.44) | MEN1KMT2AMAPTRAB9AHTT | |
| SCHEMBL11821784 | 0.78 | MAPT (0.48) | GAAMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11827688 | 0.77 | EPHX2 (0.41) | GAAMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL10817008 | 0.73 | GOT1 (0.41) | GAAMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL11826081 | 0.72 | GOT1 (0.38) | MAPTRAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL30683210 | 0.72 | PDPK1 (0.59) | GAAMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL26618968 | 0.72 | PDPK1 (0.59) | GAAMEN1KMT2AL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11824418 | 0.71 | GOT1 (0.38) | MAPTRAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL14280707 | 0.70 | GAA (0.59) | GAAMEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |