Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594840 | 0.81 | GFER (0.48) | ALDH1A1RAB9AS1PR2S1PR4S1PR1 | |
| SCHEMBL11825954 | 0.81 | S1PR2 (0.47) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL27820206 | 0.81 | PPARG (0.51) | S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL11837707 | 0.81 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1RAB9APTGS1PTGS2 | |
| SCHEMBL28741604 | 0.81 | GRIK1 (0.50) | ALDH1A1L3MBTL1RAB9APTGS1PTGS2 | |
| SCHEMBL8593573 | 0.79 | ESR1 (0.50) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL233440 | 0.79 | CNR2 (0.50) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL233441 | 0.79 | CNR2 (0.50) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL360781 | 0.79 | CNR2 (0.50) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL17923351 | 0.79 | IDO1 (0.45) | ALDH1A1L3MBTL1RAB9ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |