Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830964 | 0.85 | TSHR (0.45) | ALDH1A1L3MBTL1RAB9ANPC1PTGS1 | |
| SCHEMBL9492547 | 0.84 | PPARG (0.51) | — | |
| SCHEMBL11823101 | 0.83 | PTGS2 (0.54) | EPHX1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL11826787 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP2C9AKR1C3TSHR | |
| SCHEMBL11835552 | 0.82 | PPARG (0.47) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL11827938 | 0.82 | FFAR1 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11827137 | 0.81 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27808300 | 0.80 | ANPEP (0.43) | ALDH1A1TSHR | |
| SCHEMBL7372199 | 0.80 | PPARG (0.50) | RAB9ASMN1; SMN2HTTNPC1TSHR | |
| SCHEMBL3433828 | 0.80 | PPARG (0.50) | RAB9ASMN1; SMN2HTTNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |