Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP5 | P24593 | 8/20 | 0.47 |
| ▸ | IGFBP3 | P17936 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.39 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.39 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.39 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823904 | 0.94 | IGFBP5 (0.46) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2907215 | 0.87 | IGFBP5 (0.42) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2904707 | 0.87 | IGFBP5 (0.50) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2908228 | 0.87 | IGFBP5 (0.50) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL975885 | 0.84 | IGFBP5 (0.43) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2908985 | 0.83 | ALOX15 (0.48) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2905794 | 0.83 | IGFBP5 (0.46) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2910842 | 0.82 | ALOX15 (0.56) | IGFBP5IGFBP3ALOX15TSHRALDH1A1 | |
| Transtorine SCHEMBL22979 | 0.82 | ALOX15 (0.60) | IGFBP5IGFBP3ALOX15TSHRMGAM | |
| Transtorine SCHEMBL17596601 | 0.82 | ALOX15 (0.60) | IGFBP5IGFBP3ALOX15TSHRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984551-A | Pharmaceutical compositions comprising pyridoquinoline derivatives and the use thereof | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1976-10-05 | — | — | US | disclosed |