Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11815796 | 0.98 | MAPT (0.49) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11815797 | 0.98 | MAPT (0.49) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6938029 | 0.85 | NR4A1 (0.56) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9210472 | 0.82 | MAPT (0.67) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3867884 | 0.79 | MAPT (0.49) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3047673 | 0.78 | PLK1 (0.59) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL15784370 | 0.78 | ALDH1A1 (0.61) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23158247 | 0.76 | ALDH5A1 (0.57) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11822730 | 0.76 | ALDH1A1 (0.53) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29629277 | 0.76 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931152-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |