Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374428 | 0.88 | MAPT (0.58) | MAPTSMN1; SMN2TDP1NPSR1TSHR | |
| SCHEMBL25802136 | 0.85 | MAPT (0.53) | MAPTSMN1; SMN2TDP1FFAR1NPSR1 | |
| SCHEMBL4611029 | 0.85 | ALDH1A1 (0.68) | MAPTSMN1; SMN2TDP1FFAR1TSHR | |
| SCHEMBL1684613 | 0.85 | TSHR (0.74) | MAPTFFAR1NPSR1TSHRALDH1A1 | |
| SCHEMBL6325229 | 0.84 | LMNA (0.76) | MAPTSMN1; SMN2TDP1TSHRALDH1A1 | |
| SCHEMBL24326607 | 0.82 | ALDH1A1 (0.77) | MAPTTDP1FFAR1TSHRALDH1A1 | |
| SCHEMBL6527881 | 0.80 | NOTUM (0.70) | MAPTSMN1; SMN2TDP1NPSR1TSHR | |
| SCHEMBL8114549 | 0.80 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2TDP1NPSR1TSHR | |
| SCHEMBL10312555 | 0.80 | TSHR (0.56) | MAPTSMN1; SMN2TDP1FFAR1NPSR1 | |
| SCHEMBL10925607 | 0.79 | CXCL8 (0.43) | MAPTSMN1; SMN2FFAR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994907-A | Coumarin derivatives, their preparation and their use as optical brightening agents | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-11-30 | — | — | US | disclosed |