Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829509 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1CYP1A2POLB | |
| SCHEMBL11833616 | 0.79 | DPP4 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL10687876 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP1A2HPGDCYP2C19 | |
| SCHEMBL10687014 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP1A2HPGDCYP2C19 | |
| SCHEMBL10667965 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP1A2HPGDCYP2C19 | |
| SCHEMBL11827363 | 0.76 | TSHR (0.48) | ALDH1A1TSHRTDP1CYP1A2LMNA | |
| SCHEMBL11832023 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CYP1A2MAPT | |
| SCHEMBL11824543 | 0.73 | KMT2A (0.47) | CYP2C19KMT2A | |
| SCHEMBL4658040 | 0.73 | POLB (0.53) | ALDH1A1TSHRCYP1A2POLBCYP2C19 | |
| SCHEMBL10416252 | 0.73 | GRM8 (0.53) | ALDH1A1TSHRCYP1A2POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |