Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832023 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP1A2TSHR | |
| SCHEMBL11837592 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11829891 | 0.84 | HRH2 (0.46) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11829514 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP1A2TSHRPOLB | |
| SCHEMBL11823516 | 0.80 | MAOB (0.54) | ALDH1A1KMT2AMMP2MMP9MMP12 | |
| SCHEMBL11823662 | 0.79 | MMP12 (0.58) | TSHRGAAMMP2MMP9MMP12 | |
| SCHEMBL11757662 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1ADAMTS4CYP1A2RAB9A | |
| SCHEMBL11827360 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11790626 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL29050942 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1ADAMTS4RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |