Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | MPI | P34949 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422063 | 0.76 | MAPT (0.42) | MAPTALDH1A1HTTNPSR1PKM | |
| SCHEMBL49743 | 0.76 | MAOA (0.37) | MAPTALDH1A1HTTNPSR1PKM | |
| SCHEMBL7039952 | 0.68 | IDO1 (0.38) | MAPTALDH1A1LMNAMAPK1TDP1 | |
| SCHEMBL11815995 | 0.67 | PABPC1 (0.46) | MAPTALDH1A1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL8402800 | 0.67 | IDO1 (0.36) | IDO1TDO2NSD2DNMT1 | |
| SCHEMBL5517104 | 0.66 | MAPT (0.39) | MAPTALDH1A1HTTNPSR1PKM | |
| SCHEMBL22642297 | 0.64 | MAPT (0.32) | MAPTALDH1A1HTTNPSR1PKM | |
| SCHEMBL5612308 | 0.64 | HPGD (0.38) | MAPTALDH1A1LMNAMAPK1TDP1 | |
| SCHEMBL17581080 | 0.63 | — | — | |
| SCHEMBL11835737 | 0.62 | MAPT (0.42) | MAPTALDH1A1HTTNPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984402-A | Indoanilines for dyeing keratinous fibers | L'OREAL (FR) | 1976-10-05 | — | — | US | disclosed |