Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675635 | 0.73 | HSD17B10 (0.43) | HSD17B10ALDH1A1KDM4EMAPTMEN1 | |
| Karbutilate SCHEMBL125025 | 0.66 | TP53 (0.51) | ALDH1A1MEN1KMT2AMAPK1TP53 | |
| Karbutilate SCHEMBL29512628 | 0.66 | TP53 (0.51) | ALDH1A1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL5879426 | 0.65 | KDM4E (0.44) | HSD17B10ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL9771547 | 0.65 | KDM4E (0.48) | HSD17B10ALDH1A1KDM4EMAPTELANE | |
| SCHEMBL30295469 | 0.63 | ALDH1A1 (0.63) | ALDH1A1MAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL1123855 | 0.63 | ALDH1A1 (0.63) | ALDH1A1MAPTL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL9860877 | 0.63 | KDM4E (0.41) | HSD17B10ALDH1A1KDM4EMAPTELANE | |
| SCHEMBL3837851 | 0.62 | MAPT (0.52) | ALDH1A1MAPTHTTTP53 | |
| SCHEMBL27831985 | 0.62 | MAPK3 (0.48) | HSD17B10ALDH1A1MAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989508-A | Substituted nitroanilines and ureas as herbicidal mixtures | BASF AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |