Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835181 | 0.81 | KDM4E (0.37) | ALDH1A1SMN1; SMN2MAPTMEN1LMNA | |
| SCHEMBL11835413 | 0.81 | PTPN1 (0.42) | PTPN1ALDH1A1SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL11827151 | 0.77 | PTPN1 (0.43) | PTPN1ALDH1A1SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL11824491 | 0.76 | MME (0.44) | MMEPAK1AKR1C3AKR1C2DPP4 | |
| SCHEMBL11830204 | 0.75 | MAOB (0.41) | PTPN1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11841294 | 0.74 | KDM4E (0.39) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11847739 | 0.73 | KDM4E (0.38) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL11837141 | 0.73 | ALDH1A1 (0.43) | PTPN1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL11827580 | 0.73 | ALDH1A1 (0.43) | PTPN1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL11826415 | 0.72 | KMT2A (0.50) | PTPN1ALDH1A1SMN1; SMN2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |