Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830261 | 0.86 | PRKAG1 (0.37) | FFAR1AKR1C3AKR1C2 | |
| SCHEMBL11825640 | 0.85 | FFAR1 (0.44) | MMEFFAR1 | |
| SCHEMBL11821679 | 0.85 | MME (0.40) | MMECYP2A6DHODHHCAR2DPP4 | |
| SCHEMBL11824498 | 0.82 | CDC25A (0.37) | MMERXRARXRBNR4A2FFAR1 | |
| SCHEMBL11827349 | 0.79 | MME (0.49) | MMECYP2A6HCAR2RXRARXRB | |
| SCHEMBL11760088 | 0.79 | MME (0.49) | MMECYP2A6HCAR2DPP4DPP7 | |
| SCHEMBL11840116 | 0.78 | CYP2A6 (0.44) | MMECYP2A6DHODHHCAR2DPP4 | |
| SCHEMBL11830217 | 0.76 | PTPN1 (0.37) | MMEDPP4DPP7AKR1C3AKR1C2 | |
| SCHEMBL11837111 | 0.75 | MMP2 (0.45) | FFAR1 | |
| SCHEMBL11829227 | 0.75 | PTGS2 (0.45) | MMEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |