Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404989 | 1.00 | IAPP (0.71) | IAPPLMNAMAPTPTGER1PTGER4 | |
| SCHEMBL9658945 | 0.85 | PTGER3 (0.71) | IAPPMAPTPTGER1PTGER4PTGER3 | |
| SCHEMBL11830587 | 0.85 | PTGER3 (0.71) | IAPPMAPTPTGER1PTGER4PTGER3 | |
| SCHEMBL26046362 | 0.83 | IAPP (1.00) | IAPPLMNAMAPTKDM4EGLA | |
| SCHEMBL7177478 | 0.83 | IAPP (1.00) | IAPPLMNAMAPTKDM4EGLA | |
| SCHEMBL2834883 | 0.82 | MAPT (0.66) | IAPPLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL31422587 | 0.82 | MAPT (0.66) | IAPPLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL14279409 | 0.82 | MAPT (0.66) | IAPPLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL7899013 | 0.82 | MAPT (0.66) | IAPPLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL13177051 | 0.82 | PTGER1 (0.56) | IAPPLMNAMAPTPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079747-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LTD (GB) | 2011-03-09 | — | — | EP | disclosed |
| EP-2079747-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | Pfizer Limited (GB) | 2009-07-22 | — | — | EP | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| WO-2008044127-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | IAPP 1485/4885LMNA 1543/4885MAPT 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.