Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822578 | 0.75 | ALDH1A1 (0.47) | ALDH1A1ESR1CYP3A4ESR2FFAR1 | |
| SCHEMBL11056007 | 0.70 | CYP2C9 (0.46) | ALDH1A1ESR1CYP3A4ESR2FFAR1 | |
| SCHEMBL8532534 | 0.68 | SMN1; SMN2 (0.53) | ALDH1A1FFAR1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL11827986 | 0.68 | SLC13A5 (0.51) | FFAR1LMNAABCC4GAATSHR | |
| SCHEMBL11508350 | 0.67 | HIF1A (0.55) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| SCHEMBL27805062 | 0.67 | ALDH1A1 (0.53) | ALDH1A1ESR1CYP3A4ESR2FFAR1 | |
| Biphenyl SCHEMBL4132218 | 0.67 | FFAR1 (0.71) | ALDH1A1FFAR1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL75391 | 0.67 | ALDH1A1 (0.72) | ALDH1A1ESR1CYP3A4ESR2FFAR1 | |
| SCHEMBL1682512 | 0.67 | HIF1A (0.53) | ALDH1A1ESR1CYP3A4ESR2FFAR1 | |
| Bicarbonate SCHEMBL27490121 | 0.66 | CYP2C9 (0.57) | SMN1; SMN2LMNARAB9ACYP2C9RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |