Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842979 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1ADAMTS4CYP1A2MEN1 | |
| SCHEMBL11672909 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TDP1ADAMTS4CYP1A2ACHE | |
| SCHEMBL11845899 | 0.80 | PPARG (0.45) | ALDH1A1MEN1KMT2APTGS2TSHR | |
| SCHEMBL11851792 | 0.80 | PTGS2 (0.42) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL11834426 | 0.80 | HPGD (0.46) | ALDH1A1ADAMTS4CYP1A2MEN1KMT2A | |
| SCHEMBL11833272 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ADAMTS4CYP1A2MEN1KMT2A | |
| SCHEMBL11842923 | 0.79 | PTGS1 (0.47) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL11840116 | 0.79 | CYP2A6 (0.44) | TDP1MEN1KMT2ACYP2C19PTGS2 | |
| SCHEMBL11845939 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL11844932 | 0.79 | LTB4R2 (0.46) | MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |