Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830412 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRADAMTS4 | |
| SCHEMBL11846449 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRMAPTNPC1 | |
| SCHEMBL7785924 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1TSHRADAMTS4GSK3A | |
| SCHEMBL11821088 | 0.78 | LMNA (0.47) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL11827360 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRADAMTS4GSK3A | |
| SCHEMBL11824795 | 0.76 | ADAMTS4 (0.52) | ALDH1A1TDP1TSHRADAMTS4MEN1 | |
| SCHEMBL11831724 | 0.76 | ADAMTS4 (0.52) | ALDH1A1TDP1TSHRADAMTS4GSK3A | |
| SCHEMBL11828723 | 0.76 | MAOB (0.51) | — | |
| SCHEMBL11830114 | 0.75 | PPARG (0.51) | — | |
| SCHEMBL11825638 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |