Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825061 | 0.77 | KDM4E (0.59) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL9770532 | 0.77 | ALOX15 (0.50) | MAPTTHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL11828387 | 0.77 | SMN1; SMN2 (0.50) | KMT2ATDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL1708814 | 0.76 | KMT2A (0.65) | KMT2AMAPTTHRBTDP1MEN1 | |
| Thiourea SCHEMBL27799662 | 0.73 | MAPT (0.60) | KMT2AMAPTTHRBTDP1MEN1 | |
| SCHEMBL107833 | 0.71 | KMT2A (0.95) | KMT2AMAPTTHRBTDP1MEN1 | |
| SCHEMBL9580943 | 0.71 | GAA (0.55) | KMT2AMAPTTHRBTDP1MEN1 | |
| SCHEMBL165079 | 0.70 | MAPT (0.46) | MAPTTDP1POLBALDH1A1CYP3A4 | |
| SCHEMBL31253333 | 0.70 | MAPT (0.46) | MAPTTDP1POLBALDH1A1CYP3A4 | |
| SCHEMBL28043716 | 0.70 | RECQL (0.57) | KMT2AMAPTTHRBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981883-A | Manufacture of 3-amino-2,1-benzisothiazoles | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |