SCHEMBL165079

SCHEMBL165079

NC(=S)c1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 3/20 0.45
CYP3A4 P08684 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
ALDH1A1 P00352 7/20 0.45
HSD17B10 Q99714 7/20 0.45
CFTR P13569 1/20 0.45
TSHR P16473 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 2/20 0.38
TP53 P04637 2/20 0.37
MMP2 P08253 1/20 0.37
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
IKBKB O14920 1/20 0.36
POLB P06746 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31253333 1.00 MAPT (0.46) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL609919 0.83 ALDH1A1 (0.42) MAPTGAAALOX15ALDH1A1HSD17B10
SCHEMBL30085683 0.80 CD44 (0.41) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL975567 0.79 MAPT (0.52) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL8497588 0.78 ALOX15 (0.50) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL9628769 0.77 MAPT (0.45) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL5830365 0.77 ALDH1A1 (0.48) MAPTGAAALOX15CYP3A4SMN1; SMN2
SCHEMBL13964794 0.76 BCAT2 (0.43) MAPTGAAALDH1A1HSD17B10TSHR
SCHEMBL6793986 0.75 JAK2 (0.40) MAPTGAACYP3A4ALDH1A1HSD17B10
SCHEMBL2494996 0.75 ALOX15 (0.53) MAPTGAAALOX15CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104487439-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2017-06-09 CN claimed
CN-103109816-A Thiobenzamide compounds and application thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2013-05-22 CN claimed
CN-112047899-A Method for synthesizing 3-substituted aminobenzo [ c ] isothiazole derivative 成都睿智化学研究有限公司 2020-12-08 CN disclosed
CN-104487439-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2017-06-09 CN disclosed
CN-104487439-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2017-06-09 CN disclosed
CN-104487439-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2017-06-09 CN disclosed
CN-103857666-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2016-12-14 CN disclosed
CN-103857666-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2016-12-14 CN disclosed
EP-2903439-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-12 EP disclosed
EP-2903437-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS BASF SE (DE) 2015-08-12 EP disclosed
EP-2903441-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS BASF SE (DE) 2015-08-12 EP disclosed
US-5015740-A Psychological disorders JANSSEN PHARMACEUTICA N.V. (BE) 1991-05-14 US disclosed
US-4957916-A DISORDERS CONNECTED WITH DOPAMINE AND/OR SEROTONIN RELEASE JANSSEN PHARMACEUTICA N.V. (BE) 1990-09-18 US disclosed
CN-1040194-A Psycholeptic 3-piperazinyl indole derivatives JANSSEN PHARMACEUTICA NV (BE) 1990-03-07 CN disclosed
EP-0353821-A2 Antipsychotic 3-piperazinyl-benzazole derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-02-07 EP disclosed
US-4804663-A PSYCHOLOGICAL DISORDERS JANSSEN PHARMACEUTICA N.V. (BE) 1989-02-14 US disclosed
EP-0196132-A2 1,2-Benzisoxazol-3-yl and 1,2-benzisothiazol-3-yl derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1986-10-01 EP disclosed
US-4233113-A USED FOR PRINTED CIRCUITS DART INDUSTRIES INC. (US) 1980-11-11 US disclosed
US-4012305-A DIMERIZATION OF STYRENES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-03-15 US disclosed
US-3981883-A Manufacture of 3-amino-2,1-benzisothiazoles BASF AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed