Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071051 | 0.83 | TDP1 (0.50) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL7168641 | 0.83 | ALDH1A1 (0.50) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL14800110 | 0.80 | ALDH1A1 (0.48) | TDP1SMN1; SMN2TP53MAPTHTT | |
| SCHEMBL27456798 | 0.78 | ALOX15 (0.50) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL688411 | 0.78 | MAPT (0.56) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL24629842 | 0.78 | ALOX15 (0.50) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL11044723 | 0.78 | CSNK2A1 (0.55) | ALOX15TDP1TP53MAPTHTT | |
| SCHEMBL11162396 | 0.78 | ALOX15 (0.45) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL11265101 | 0.78 | ALOX15 (0.45) | ALOX15TDP1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL11831729 | 0.77 | KMT2A (0.54) | ALOX15TDP1CYP3A4THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |
| US-3981883-A | Manufacture of 3-amino-2,1-benzisothiazoles | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |