Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | SI | P14410 | 1/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916356 | 0.84 | RAB9A (0.48) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL1544650 | 0.83 | ALDH1A1 (0.65) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL12082222 | 0.83 | RAB9A (0.69) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL2248581 | 0.83 | KDM4E (0.69) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL30038044 | 0.77 | FABP6 (0.63) | NPC1RAB9AKDM4EMAPTTDP1 | |
| SCHEMBL1170803 | 0.77 | FABP6 (0.63) | NPC1RAB9AKDM4EMAPTTDP1 | |
| SCHEMBL28601354 | 0.77 | ALDH1A1 (1.00) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL1391679 | 0.77 | KDM4E (0.78) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL6420845 | 0.77 | ALDH1A1 (0.65) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL2249384 | 0.77 | ALDH1A1 (1.00) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932395-A | ANTIPYRETIC, ANTIPHLOGISTIC AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1976-01-13 | — | — | US | disclosed |