Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714350 | 0.84 | CCR1 (0.46) | CBFBCCR1CCR5CCR8NPC1 | |
| SCHEMBL477370 | 0.79 | KDM4E (0.50) | CBFBCCR1CCR5CCR8NPC1 | |
| SCHEMBL5990815 | 0.78 | CYP19A1 (0.56) | CCR1CCR5CCR8NPC1MAPT | |
| SCHEMBL30090507 | 0.78 | CYP19A1 (0.56) | CCR1CCR5CCR8NPC1MAPT | |
| SCHEMBL7576751 | 0.78 | CCR1 (0.53) | CBFBCCR1CCR5CCR8NPC1 | |
| Methane SCHEMBL28035176 | 0.78 | KDM4E (0.48) | CBFBCCR1CCR5CCR8NPC1 | |
| Methane SCHEMBL28337075 | 0.76 | KDM4E (0.46) | CBFBCCR1CCR5CCR8NPC1 | |
| SCHEMBL5328289 | 0.76 | CCR1 (0.52) | CBFBCCR1CCR5CCR8NPC1 | |
| SCHEMBL29901533 | 0.76 | CCR1 (0.52) | CBFBCCR1CCR5CCR8NPC1 | |
| SCHEMBL28115227 | 0.76 | CCR1 (0.52) | CBFBCCR1CCR5CCR8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940386-A | Substituted cinnamoyl-piperazine-pyridyl compound | CERMOL S.A. | 1976-02-24 | — | — | US | disclosed |