Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28035176 | 0.98 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| Methane SCHEMBL28337075 | 0.96 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2490120 | 0.89 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL10358887 | 0.85 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11066304 | 0.84 | PDCD1 (0.59) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL24888335 | 0.83 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL21666537 | 0.83 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL10358913 | 0.83 | CBFB (0.44) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29065472 | 0.80 | TYRO3 (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4600282 | 0.80 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237467-B | A kind of preparation method of doxylamine succinate | 南京济群医药科技股份有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-107056685-A | Method for synthesizing doxylamine succinate | 珠海市海瑞德生物科技有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-116063137-B | Synthesis method for synthesizing chiral 2-pyridyl aryl methanol by iridium catalysis | 中国科学院大连化学物理研究所 | 2024-07-16 | — | — | CN | disclosed |
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-05-23 | — | — | US | disclosed |
| CN-116199621-A | Synthesis method of chiral pyridine-2, 6-diol | 中国科学院大连化学物理研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-116063137-A | Synthesis method for synthesizing chiral 2-pyridyl aryl methanol by iridium catalysis | 中国科学院大连化学物理研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-106905228-B | A kind of method that ruthenium catalysis prepares substituted aryl first alcohol compound | 浙江工业大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-105237467-B | A kind of preparation method of doxylamine succinate | 南京济群医药科技股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-105237467-B | A kind of preparation method of doxylamine succinate | 南京济群医药科技股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-107056685-A | Method for synthesizing doxylamine succinate | 珠海市海瑞德生物科技有限公司 | 2017-08-18 | — | — | CN | disclosed |
| EP-0798313-B1 | OLEFIN POLYMERIZATION CATALYST | ASAHI CHEMICAL IND (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5854249-A | Opioid diarylmethylpiperazines and piperidines | DELTA PHARMACEUTICALS, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0798313-A1 | OLEFIN POLYMERIZATION CATALYST | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |
| US-5658908-A | RECEPTOR BINDING SPECIES FOR MEDIATING ANALGESIA, COMBATTING DRUG ADDICTION, DRUG OVERDOSE | DELTA PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0649414-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993015062-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| US-4900751-A | 2-Pyridinyl-phenyl-sulphinyl-and-phenyl-thio-benzimidazoles having antiflammatory or gastic acid secretion inhibition activity | FISONS PLC (GB) | 1990-02-13 | — | — | US | disclosed |
| US-4851419-A | Certain 2-pyridinyl-phenylsulfinyl-benzoxazoles, the corresponding benzothiazoles or benzimidazoles having anti-inflammatory or gastric acid secretion inhibition activity | FISONS PLC (GB) | 1989-07-25 | — | — | US | disclosed |
| EP-0220053-A2 | Benzimidazoles, benzoxazoles, benzothiazoles and their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1987-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | MPO, XDH, EPX | KDM4E 3038/4885LMNA 2643/4885CCR1 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.