Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23571859 | 0.83 | USP2 (0.65) | HSD17B10TP53TSHRALDH1A1USP2 | |
| SCHEMBL29823082 | 0.83 | USP2 (0.65) | HSD17B10TP53TSHRALDH1A1USP2 | |
| SCHEMBL26310974 | 0.82 | PARP1 (0.53) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL7468675 | 0.82 | L3MBTL1 (0.63) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL23534259 | 0.82 | L3MBTL1 (0.49) | HSD17B10TP53PARP1MAPK1TSHR | |
| SCHEMBL10678266 | 0.80 | HSD17B10 (0.51) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL5670852 | 0.80 | PARP1 (0.60) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL532921 | 0.79 | USP2 (0.48) | HSD17B10TP53PARP1MAPK1TSHR | |
| SCHEMBL26311050 | 0.79 | L3MBTL1 (0.53) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL26654694 | 0.79 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2PARP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| US-3935203-A | ANALGESICS, ANTI-OEDEMATOUS | CERPHA (FR) | 1976-01-27 | — | — | US | disclosed |