Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678266 | 0.83 | HSD17B10 (0.51) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL18209180 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10MAPK1TSHRALDH1A1 | |
| SCHEMBL3597209 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL2101384 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL7476434 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10TP53MAPK1TSHR | |
| SCHEMBL20414554 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL7460746 | 0.83 | L3MBTL1 (0.67) | L3MBTL1HSD17B10TSHRALDH1A1USP2 | |
| SCHEMBL17055837 | 0.83 | L3MBTL1 (0.63) | L3MBTL1HSD17B10MAPK1TSHRALDH1A1 | |
| SCHEMBL11831795 | 0.82 | HSD17B10 (0.61) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL13061281 | 0.81 | L3MBTL1 (0.60) | L3MBTL1HSD17B10TP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |