Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494319 | 0.82 | HTT (0.45) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL17382014 | 0.82 | LMNA (0.41) | HTTGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL21808338 | 0.81 | EPHX2 (0.57) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL15080872 | 0.79 | CCNC (0.48) | L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL23174789 | 0.77 | LMNA (0.43) | HTTGAAALDH1A1EPHX2LMNA | |
| SCHEMBL13031176 | 0.77 | HTT (0.38) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL16160355 | 0.75 | L3MBTL1 (0.40) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL3514895 | 0.75 | L3MBTL1 (0.43) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL15156847 | 0.75 | L3MBTL1 (0.49) | HTTGAAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL12121229 | 0.75 | MEN1 (0.44) | HTTGAAL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| US-3957480-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1976-05-18 | — | — | US | disclosed |