Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832826 | 0.72 | CHEK1 (0.49) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL1997012 | 0.67 | MGAM (0.53) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL11826941 | 0.66 | MMP2 (0.41) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL11826221 | 0.66 | CHEK1 (0.37) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL3344653 | 0.65 | MAPT (0.53) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL29448938 | 0.65 | PKM (0.44) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL11833908 | 0.63 | MMP2 (0.42) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL25028187 | 0.62 | MMP2 (0.46) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL3293364 | 0.62 | MMP2 (0.46) | FYNCHEK1AURKADAPK3JAK2 | |
| SCHEMBL11825948 | 0.62 | BRD4 (0.47) | FYNCHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957766-A | BACTERIOSTATS, BACTERICIDES | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-05-18 | — | — | US | disclosed |