Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | SI | P14410 | 5/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2506896 | 0.81 | MMP2 (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL26135464 | 0.80 | CHEK1 (0.44) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11882511 | 0.78 | TDP1 (0.40) | ALDH1A1MEN1MAPTKMT2AMMP2 | |
| SCHEMBL25028187 | 0.76 | MMP2 (0.46) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL16151139 | 0.73 | MMP2 (0.40) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL3344653 | 0.73 | MAPT (0.53) | ALDH1A1MEN1MAPTKMT2AMMP2 | |
| SCHEMBL2487170 | 0.72 | MAPT (0.41) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11364130 | 0.71 | ALDH1A1 (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL31758552 | 0.71 | ALDH1A1 (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11833908 | 0.71 | MMP2 (0.42) | GAAALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187182-A1 | PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-05 | — | — | WO | claimed |
| US-20080086214-A1 | Medical device having a sleeve valve with bioactive agent | WILSON-COOK MEDICAL INC. (US) | 2008-04-10 | — | — | US | claimed |
| WO-2023187182-A1 | PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-05 | — | — | WO | disclosed |
| CN-110407730-B | Pyrrolidone herbicides | FMC 公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114805243-B | Preparation of 1,3, 4-thiadiazole and 1,3, 4-selenadiazole | 兰州大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-114805243-A | Preparation of 1,3, 4-thiadiazole and 1,3, 4-selenadiazole | 兰州大学 | 2022-07-29 | — | — | CN | disclosed |
| US-8881365-B2 | Implantable graft device having treated yarn and method for making same | COOK MEDICAL TECHNOLOGIES LLC (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2788041-A1 | ANTIFUNGAL CATHETER | Rochester Medical Corporation (US) | 2014-10-15 | — | — | EP | disclosed |
| CN-104053460-A | ANTIFUNGAL CATHETER | ROCHESTER MEDICAL CORP | 2014-09-17 | — | — | CN | disclosed |
| WO-2013086195-A1 | ANTIFUNGAL CATHETER | ROCHESTER MEDICAL CORPORATION (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20130150828-A1 | ANTIFUNGAL CATHETER | ROCHESTER MEDICAL CORPORATION (US) | 2013-06-13 | — | — | US | disclosed |
| EP-0617631-A4 | SUSTAINED-RELEASE BACTERICIDAL CANNULA. | ROCHESTER MEDICAL CORP (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0617631-A1 | SUSTAINED-RELEASE BACTERICIDAL CANNULA | ROCHESTER MEDICAL CORPORATION (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5261896-A | Sustained release bactericidal cannula | ROCHESTER MEDICAL CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| WO-1993011821-A1 | SUSTAINED-RELEASE BACTERICIDAL CANNULA | ROCHESTER MEDICAL CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |
| US-4684728-A | Solubilizing biologically active compounds with reactive hydrogen atoms | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-04 | — | — | US | disclosed |
| EP-0017772-B1 | METHOD OF IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE AGENTS IN WATER AND IN LOWER ALIPHATIC ALCOHOLS, AND COMPOUNDS HAVING AN IMPROVED SOLUBILITY | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
| EP-0014263-B1 | METHOD OF IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE AGENTS IN WATER AND IN LOWER ALIPHATIC ALCOHOLS, AND COMPOUNDS HAVING AN IMPROVED SOLUBILITY | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0017772-A1 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-10-29 | — | — | EP | disclosed |
| EP-0014263-A2 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |