Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824022 | 0.88 | HRH2 (0.46) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11827539 | 0.87 | PTPN1 (0.42) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11839171 | 0.83 | ALDH1A1 (0.53) | HRH2HRH1ALDH1A1TDP1PTPN1 | |
| SCHEMBL11845170 | 0.82 | HRH2 (0.49) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11835413 | 0.82 | PTPN1 (0.42) | ALDH1A1L3MBTL1PTPN1MAPTKDM4E | |
| SCHEMBL10347130 | 0.81 | MAPT (0.55) | ALDH1A1TDP1L3MBTL1MAPTKDM4E | |
| SCHEMBL11828483 | 0.81 | PTPN1 (0.46) | ALDH1A1L3MBTL1PTPN1MAPTKDM4E | |
| SCHEMBL11828669 | 0.79 | HRH2 (0.48) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11842360 | 0.79 | HRH2 (0.50) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11828776 | 0.78 | HRH2 (0.46) | HRH2HRH1ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |