Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845170 | 0.86 | HRH2 (0.49) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11824022 | 0.82 | HRH2 (0.46) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11835254 | 0.81 | PPARG (0.46) | ALDH1A1TDP1L3MBTL1KDM4ERAB9A | |
| SCHEMBL11842494 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TDP1ADAMTS4MAPTLMNA | |
| SCHEMBL11842785 | 0.80 | MAPT (0.52) | ALDH1A1L3MBTL1GAAKDM4ERAB9A | |
| SCHEMBL11847061 | 0.80 | MMP8 (0.39) | ALDH1A1TDP1L3MBTL1KDM4ERAB9A | |
| SCHEMBL11836617 | 0.80 | CA12 (0.42) | ALDH1A1TDP1L3MBTL1ADAMTS4KDM4E | |
| SCHEMBL11833045 | 0.79 | HRH2 (0.46) | HRH2HRH1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11790207 | 0.79 | CASP1 (0.47) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11837748 | 0.79 | MAPT (0.49) | ALDH1A1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |