Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827914 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP1A2TSHRFBP1 | |
| SCHEMBL11757234 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11833045 | 0.83 | HRH2 (0.46) | ALDH1A1TDP1ADAMTS4MAPTLMNA | |
| SCHEMBL11839175 | 0.82 | CYP1A2 (0.48) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11827349 | 0.80 | MME (0.49) | ALDH1A1HPGD | |
| SCHEMBL11790626 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11838193 | 0.79 | FFAR1 (0.50) | ALDH1A1ADAMTS4CYP1A2TSHRLMNA | |
| SCHEMBL10347131 | 0.78 | CYP3A4 (0.48) | ALDH1A1TDP1CYP1A2TSHRMAPT | |
| SCHEMBL11760551 | 0.76 | LMNA (0.59) | ALDH1A1TDP1ADAMTS4CYP1A2FBP1 | |
| SCHEMBL11842494 | 0.75 | ALDH1A1 (0.62) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |