Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.40 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836974 | 0.85 | MMP12 (0.47) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11829367 | 0.80 | SRR (0.51) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11834777 | 0.80 | MMP12 (0.48) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11828675 | 0.80 | MMP12 (0.50) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11828625 | 0.78 | MMP12 (0.46) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11828266 | 0.78 | MMP12 (0.46) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL7290221 | 0.75 | CPA1 (0.50) | MMP12MMP2MMP9PTGS1CPA1 | |
| SCHEMBL11835427 | 0.75 | MMEL1 (0.48) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11833110 | 0.75 | HPGD (0.46) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11836431 | 0.75 | MMP12 (0.43) | MMP12MMP2MMP9MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |