Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426350 | 0.84 | CA12 (0.51) | TSHRTDP1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL128776 | 0.84 | CA12 (0.53) | TSHRSMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL9187932 | 0.83 | TSHR (0.44) | TSHRTDP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11839343 | 0.83 | ALOX15 (0.46) | TSHRSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL5394487 | 0.82 | LMNA (0.39) | TSHRSMN1; SMN2ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL11088791 | 0.81 | TDP1 (0.44) | TSHRTDP1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL27470832 | 0.81 | HPGD (0.47) | TSHRTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10399338 | 0.80 | RAB9A (0.44) | TSHRL3MBTL1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8900698 | 0.80 | RAB9A (0.47) | TDP1L3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11422463 | 0.78 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2ALDH1A1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932423-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES (JA) | 1976-01-13 | — | — | US | disclosed |