Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MYOC | Q99972 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831461 | 0.85 | MEN1 (0.53) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11839569 | 0.83 | PDE7A (0.60) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11833629 | 0.81 | PDE7A (0.53) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11832321 | 0.80 | MEN1 (0.62) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11826914 | 0.79 | MAPT (0.65) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11837503 | 0.77 | ALDH1A1 (0.59) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11830737 | 0.75 | MEN1 (0.82) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL10977063 | 0.75 | TDP1 (0.56) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL11832700 | 0.75 | MEN1 (0.59) | MEN1KMT2AGAAPKMMAPT | |
| SCHEMBL11780140 | 0.73 | ALDH3A1 (0.54) | MEN1KMT2AGAAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |