Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843523 | 0.94 | MEN1 (0.32) | SIGMAR1 | |
| SCHEMBL11851354 | 0.88 | — | — | |
| SCHEMBL11830830 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL11840331 | 0.86 | MAPT (0.37) | — | |
| SCHEMBL11840457 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL11845183 | 0.80 | CD44 (0.34) | — | |
| SCHEMBL11841300 | 0.80 | — | — | |
| SCHEMBL11844475 | 0.79 | GPR35 (0.31) | — | |
| SCHEMBL11841983 | 0.78 | — | — | |
| SCHEMBL11842221 | 0.78 | GPR35 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959488-A | 1-Substituted biguanides for treating hyperacidity or ulceration | WILLIAM H. RORER, INC. (US) | 1976-05-25 | — | — | US | disclosed |